Bridging Audiology and Psychology

%5,'*,1* $8',2/2*<$1' 36<&+2/2*< DXGLWRU\ QHUYH DQG WKH DXGLWRU\ DUHDV RI WKH EUDLQVWHP 7KHVH SRWHQWLDOV DSSHDUHG UHJDUGOHVV RI KHDUW UDWH RU EUHDWKLQJ HYHQ DIWHU UHPRYDO RI WKH RVVLFXODU FKDLQ 7KH\ FKDQJHG XQGHU DFRXVWLF VWLPXODWLRQ DQG GLG QRW GLVDSSHDU XQOHVV WKH FRFKOHD ZDV UHPRYHG 7R TXRWH IURP /LSSH¶V FRQFOXVLRQV ³ The discharge of potentials from the afferent sensory fibers plays an important role in the development of the nervous system. The evidence for this conclusion stems in large part from the finding that manipulations that alter the amount or pattern of sensory input produce abnormalities in nerve structure. ´ /LSSH KRZHYHU UDLVHG GRXEWV DERXW ZKHWKHU KLV REVHUYDWLRQV FRXOG EH H[WUDSRODWHG WR PDPPDOV EXW \HDUV ODWHU D VWXG\ E\ 7ULWVFK DQG %HUJOHV SRVWXODWHG WKH IROORZLQJ ³ Neurons in the developing auditory system fire off bursts of action potentials before the onset of hearing. This spontaneous activity promotes the survival and maturation of the auditory neurons >EROG W\SH DGGHG@ and the refinement of synaptic connections in the auditory nuclei. However, the mechanisms responsible for initiating this activity remain uncertain”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hythmic Spontaneous Activity in the Developing Avian Auditory system. /LSSH :5 0DUFK 7KH -RXUQDO RI 1HXURVFLHQFH 9RO SS Developmental regulation of spontaneous activity in the mammalian cochlea. 7ULWVFK 1 ; DQG %HUJOHV ' ( - 1HXURVFL 9RO The precise temporal pattern of pre-hearing spontaneous activity is necessary for tonotopic map refinement. &ODXVH $ HW DO 0D\ 1HXURQ 9RO SS Spontaneous activity in the developing auditory system. :DQJ + & \ %HUJOHV ' ( 2FW &HOO 7LVVXH 5HV